trial

in Health care

0.1% water-free cyclosporine solution superior to vehicle on ocular surface in dry eye disease: ESSENCE 2 trial.

by April 15, 2023, 5:27 am

Essence 2 randomized clinical trial found that usage of 0.1% water-free cyclosporine solution yielded superior results as it produced early therapeutic effects on the ocular surface when compared to vehicle in dry eye disease patients. The trial results confirmed the ESSENCE 1 trial results and were published in the journal JAMA Ophthalmology. Dry eye disease […] More
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in Health care

IV sotalol loading safe and feasible in adult patients with atrial fibrillation: DASH-AF trial

by April 12, 2023, 2:41 pm

USA: Findings from the DASH-AF trial have shown the safety and feasibility of rapid IV sotalol loading for rhythm control in patients with atrial fibrillation/flutter versus conventional oral loading with significant cost reduction. The findings were published in JACC: Clinical Electrophysiology on Feb 22, 2023. “Our findings support a practice shift from conventional 3-day PO […] More
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Flu vaccine did not meet criteria for early success in late-stage trial: Moderna

by April 12, 2023, 7:03 am

Boston: Moderna Inc said on Tuesday its experimental flu vaccine did not meet the criteria for “early success” in a late-stage trial, and its shares fell 3%. The U.S. biotech company at its vaccine day meeting in Boston also said it expects to have six major vaccines on the market in the next few years. […] More
in Health care

AstraZeneca announces positive results from ovarian cancer combo therapy trial

by April 7, 2023, 6:00 am

UK: AstraZeneca has announced positive high-level results from a planned interim analysis of the DUO-O Phase III trial. The results showed treatment with a combination of Lynparza (olaparib), Imfinzi (durvalumab), chemotherapy and bevacizumab demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) versus chemotherapy plus bevacizumab (control arm) in newly diagnosed patients […] More
in Health care

Novartis halts UK trial of anticholesterol drug Leqvio

by March 24, 2023, 9:26 am

Novartis said on Wednesday that it had decided not to move forward with ORION-17, the UK-based primary prevention trial originally planned as part of its partnership with NHS England to investigate the potential of the anti-cholesterol drug Leqvio. “After careful evaluation, we have decided not to move forward with ORION-17,” a spokesperson said in an […] More