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    Rapamycin Rescues Age-Impaired Blood Flow in Mice

    Scientists have concluded that rapamycin treatment started in early mid-life can prevent age-related blood flow impairment in the hindlimbs of wild-type, atherosclerotic, and Alzheimer’s model mice [1]. PAD and aging Peripheral artery disease (PAD) is defined as reduced blood flow to the lower limbs. Age is a major risk factor for PAD, as the disease […] More

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    Excessive Fat, Not Sugar, Leads to Obesity in Mice

    In a new study published in Endocrinology and Metabolism, researchers have shown that fat rather than sugar is the macronutrient that drives obesity and other detrimental metabolic changes if it constitutes a large proportion of dietary calories [1]. Obesity, diet, and the microbiome Obesity is associated with a dysregulation of several molecular pathways, which lead […] More