melanoma

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  • in Health care

    5-mm margins may be adequate for T1a melanoma excision near critical structures

    5-mm margins may be adequate for T1a melanoma excision near critical structures

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    Researchers have found in a new research that 5-mm margins may be adequate for T1a melanoma excision near critical structures and may not be associated with an increased risk of local recurrence. The study published in the JAMA Dermatology Melanoma guidelines recommend surgical excision with 10-mm margins for T1 melanoma. However, this procedure may be […] More

  • in Health care

    Immunotherapy response in advanced melanoma influenced by prior treatments: Study

    Immunotherapy response in advanced melanoma influenced by prior treatments: Study

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    When a patient is diagnosed with advanced melanoma, they usually are treated with immune therapies like anti-PD-1 blockade and anti-CTLA-4 blockade, in combination or alone. By blocking different proteins that diminish the effectiveness of T cells, these checkpoint inhibitors enhance the body’s immune response to cancer. Research led by scientists at UCLA Jonsson Comprehensive Cancer […] More

  • in Health care

    Novel immunotherapy delivery approach benefits some melanoma patients with leptomeningeal disease

    Novel immunotherapy delivery approach benefits some melanoma patients with leptomeningeal disease

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    A novel approach to administer intrathecal (IT) immunotherapy (directly into the spinal fluid) and intravenous (IV) immunotherapy was safe and improved survival in a subset of patients with leptomeningeal disease (LMD) from metastatic melanoma, according to interim analyses of a Phase I/Ib trial led by researchers at The University of Texas MD Anderson Cancer Center. […] More