Research published yesterday in Nature has described one way in which RNA sequencing changes in the cell with age and how this may be linked to lifespan. Transcriptional elongation Transcriptional elongation is a fundamental biological process, as it affects the basic steps involved in the production of RNA, which is responsible for executing the instructions […] More
Prior studies had found that brains lose synapses as they age, and the researchers saw this pattern in their non-human primate model, too. But when they looked at the synapses that remained, they found evidence of a breakdown in coordination between the size of boutons and the mitochondria they contained. A fundamental neuroscientific principle, the […] More
Mammals, including humans, have two main types of fat: white adipose tissue (WAT), which stores energy from excess calorie intake, and brown adipose tissue (BAT), which burns calories to produce heat to maintain body temperature. By stimulating the production of a certain type of fat cells, the effects of a slowing metabolism could be reversed, […] More
Age-related macular degeneration (AMD), is a common cause of vision loss in older adults. A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving AMD. The variants generate malformed proteins that alter the stability of the membrane attack complex (MAC), which may drive […] More
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